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Case Study · 03

Complex regional pain syndrome confined to one foot

A patient in their forties with CRPS confined to the right foot after an L3–L5 lumbar fusion complicated by intraoperative injury to the right L5 and S1 nerves. Allodynia was so severe that a bedsheet was intolerable, and the neuropathic pain followed the L5 and S1 distributions. Following a previous SCS trial elsewhere that had failed to cover the foot, a successful two-lead DRG trial at right L5 and S1 led to permanent implantation at those same targets.

At a glance

Patient
Mid 40s
Region
Right foot, L5 and S1 distribution
Procedure
Right L5 and S1 DRG stimulation
Outcome
Sustained at 12 months
Read the case
Conventional spinal cord stimulation covers the foot unreliably and shifts with posture. How can right L5 and S1 DRG targets provide stable coverage across the affected foot?

Patient names are omitted from this account. The clinical course and reported outcome describe an actual treated case and do not predict another person's response.

Clinical Summary

What the patient came in with

Presentation

Burning pain confined to the right foot across its dorsal, lateral and plantar surfaces in the right L5 and S1 distributions, with colour and temperature changes, swelling, and allodynia to light touch. Baseline pain 9/10. The patient slept with the affected foot outside the covers year-round.

Walking was limited to short distances in a loose sandal. Closed shoes had been impossible for eighteen months. Careful sensory mapping showed that the painful region crossed the right L5 and S1 territories while remaining confined to one foot.

Prior treatment

L3–L5 lumbar fusion with instrumentation, complicated by intraoperative injury to the right L5 and S1 nerves. Residual neuropathic pain progressed to CRPS of the right foot in those distributions.

Sympathetic blocks with brief relief, physical therapy limited by allodynia, mirror therapy, gabapentin, amitriptyline and topical agents. A spinal cord stimulator trial at another centre produced good calf coverage but almost none over the foot, and was abandoned.

Why two-level DRG rather than SCS

The foot sits at the distal end of overlapping dermatomal territories that conventional dorsal column stimulation reaches inconsistently — a known limitation, and one this patient had already experienced directly. The distribution here included dorsal, lateral and plantar regions rather than one narrow strip of the foot.

Targeting the right L5 and S1 dorsal root ganglia created complementary fields across those adjacent territories. The two-lead plan was selected to reduce the chance of leaving a painful gap while retaining the focal, posture-stable coverage that makes DRG stimulation useful for CRPS confined to a foot.

The dorsal root ganglion sits in the foraminal space with very little cerebrospinal fluid around it, allowing defined coverage that remains comparatively stable when the patient changes position. The ACCURATE trial specifically studied lower-limb CRPS and reported higher treatment success with DRG stimulation than with conventional SCS.

Pre-procedure evaluation

Psychological evaluation completed, as it is for every implant candidate — not to screen the patient out, but to identify untreated depression, unrealistic expectations or an unmanaged sleep problem that would blunt the result. In this case it identified a treatable anxiety disorder that was addressed before implantation.

A detailed pain map was documented before the trial and used to plan two right-sided targets: L5 for the dorsum of the foot and S1 for the lateral and plantar regions. Insurance authorisation was obtained with documentation of failed conservative care and the prior unsuccessful SCS trial.

Procedure

Two-lead placement at right L5 and S1

Two right-sided DRG leads were used to span the overlapping L5 and S1 sensory territories of the affected foot. Each lead had to be steered into the appropriate foramen, seated over its ganglion and tested as part of a combined L5–S1 coverage plan.

Procedural Imaging

Right L5 and S1 electrode positions

AP and lateral fluoroscopy show the labeled right L5 and S1 DRG electrodes alongside the pre-existing L3–L5 fusion hardware. The images document position, not symptom relief or outcome.

  • Right L5 and S1 targetsThe labels identify the right L5 and S1 DRG electrodes, with the pre-existing lumbar fusion instrumentation visible above them.
  • Transforaminal electrode positionsThe lateral view shows the labeled L5 and S1 DRG electrodes in relation to the existing lumbar fusion construct.
  1. 01

    Pain map and AP fluoroscopy

    Two-level planning

    The pre-procedure pain map was matched to the dorsal, lateral and plantar surfaces of the right foot. Right L5 and S1 were selected together so the final stimulation field would follow the painful region across both distributions.

  2. 02

    Oblique fluoroscopic view

    L5 lead placement

    A steerable sheath was directed toward the right L5 foramen, and the first lead was seated over the L5 dorsal root ganglion to establish coverage across the dorsum of the foot.

  3. 03

    Sacral foraminal view

    S1 lead placement

    The second lead was advanced to the right S1 dorsal root ganglion, extending coverage to the lateral and plantar portions of the foot that would otherwise remain vulnerable to a stimulation gap.

  4. 04

    AP and lateral fluoroscopy

    Position confirmed in two views

    AP and lateral fluoroscopy showed the right L5 and S1 DRG electrode positions in relation to the pre-existing L3–L5 fusion instrumentation.

  5. 05

    Two-lead testing

    Combined coverage confirmation

    Each lead was tested individually and then in combination. Programming was balanced across right L5 and S1 until the stimulation field matched the painful foot without unnecessary spread into the calf or the opposite side.

  6. 06

    Seven days, then permanent

    Trial then implant

    A seven-day trial with right L5 and S1 leads produced stable, clinically meaningful coverage of the painful territory. Permanent implantation followed at the same two right-sided targets, with both leads connected to a generator placed in the flank.

Follow-Up

What happened afterwards

The trial week

Allodynia reduced within forty-eight hours — the first change the patient noticed was tolerating a sock. Pain fell from 9/10 to 4/10 by day five, with improvement across the dorsal, lateral and plantar surfaces rather than in only one portion of the foot.

Programming confirmed that the right L5 and S1 leads contributed complementary coverage. Crucially, the combined field did not shift away from the foot when the patient stood, sat or lay down — the specific failure of the previous SCS trial.

Three to six months

Closed shoes tolerated by week eight. Physical therapy resumed and, for the first time, progressed — weight-bearing had previously been limited by pain rather than by strength.

Swelling and colour change improved gradually, lagging behind the pain score by several months.

Twelve months

Average pain 3/10 with allodynia largely resolved. Walking tolerance greater than a mile. Gabapentin reduced but not stopped.

One programming adjustment at month seven after a period of reduced efficacy; no revision required.

Outcome

Two-level coverage confined to the painful foot

9/10 → 3/10

Average pain at 12 months

Lead configuration
Right L5 and S1
Allodynia
Largely resolved
Footwear
Closed shoes by week 8
Revisions
None

Clinical pearl

CRPS may be confined to one foot without being confined to one dermatome. After injury to the right L5 and S1 nerves during lumbar fusion, complementary L5 and S1 DRG targets can address the dorsal, lateral and plantar territories of the affected foot. A failed SCS trial may reflect a targeting problem rather than a failure of neuromodulation itself.

Individual results vary. This case is presented for education and does not predict the outcome of any therapy in any other patient.

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